Synthesized in 1938 as a potential anticholinergic agent by the german chemist otto eisleb, its analgesic properties were first recognized by otto schaumann while working for ig farben, germany. It may also be used before and during surgery or other procedures. Many organizations have eliminated the use of meperidine entirely, so consider doing the. Meperidine pethidine versus morphine in acute pain management. Demerol is a drug used to control pain and demerol is also known as meperidine. Meperidine is used to help relieve moderate to severe pain. Full text meperidine pethidine versus morphine in acute pain. Meperidine hydrochloride injection is indicated for preoperative medication, support of anesthesia, for obstetrical analgesia, and for the management of pain severe enough to require an opioid analgesic and for which alternative treatments are inadequate.
Meperidine is most often administered intramuscularly or intravenously, due to its poor oral bioavailability, and is metabolized extensively by the liver. From the department of anaesthesia, royal victoria. Other opioids that are similar to demerol include morphine, codeine, heroin, vicodin, dilaudid and oxycontin among others. Use nitros industryleading pdf to word converter to create better quality doc files than the alternatives. A synthetic opioid, c15h21no2, used in its hydrochloride form as an analgesic and sedative. Analgesic, adjunct to anesthesia controlled substance schedule ii pregnancy risk category c action binds to and depresses opiate receptors in spinal cord and cns, altering perception of and response to pain availability injection. The drug is used to treat moderate to severe pain, help put people to sleep before an operation, and provide pain relief after. Eliminate use of meperidine meperidine, usually prescribed for pain relief, is known to have some undesirable side effects that may lead to adverse drug events ades. Meperidine is an opioid agonist and therefore has abuse potential and risk of fatal overdose from respiratory failure. Using opioid medicine during pregnancy may cause lifethreatening.
Meperidine hydrochloride synonyms, meperidine hydrochloride. This page brings back any words that contain the word or letter you enter from a large scrabble dictionary. Meperidine is a synthetic opioid widely used for treating pain. Lowering the dose or stopping meperidine injection all of a sudden may cause a greater risk of withdrawal or other severe problems. Updated with all the very latest new words and senses, this new th edition is an unparalleled resource for word lovers, word gamers, and word geeks everywhere. Meperidine mimics the actions of endogenous neuropeptides via opioid receptors, thereby producing the characteristic morphinelike effects on the muopioid receptor, including analgesia, euphoria, sedation, respiratory depression, miosis, bradycardia and physical dependence.
Meperidine demerol has been a leading mu opioid analgesic for many years. Demerol meperidine side effects, dosage, interactions drugs. Words that contain meperidine words containing meperidine. Demerol is the brand name for meperidine which is a member of the opioids drug class. It works in the brain to change how your body feels and responds to pain. Heres a list of similar words from our thesaurus that you can use instead. Classification alternate names narcotic analgesic pethidine, demerol indications for shortterm management of moderate to severe pain if normal renal, hepatic, and cns function and alternative opioids are contraindicated restricted to treatment of drug or bloodinduced rigors and postoperative shivering. Although meperidine s anticholinergic effects were demonstrated in vivo, the. The drug is used to treat moderatetosevere pain, help put people to sleep before an operation, and provide pain relief after.
Synonyms for meperidine hydrochloride in free thesaurus. On the other hand, the patients who received meperidine indicated prominent. Meperidine hydrochloride overdose occurs when someone takes more than the normal or recommended amount of this medicine. Meperidine crossword answers, clues, definition, synonyms. Demerol meperidine hydrochloride tablets 100 mg, are white, round, convex scored tablets debossed with w on one side and d over 37 on the other, and are supplied as. Pharmacokinetics of meperidine in spinal anaesthesia. Meperidine definition is a synthetic narcotic drug c15h21no2 used in the form of its hydrochloride as an analgesic, sedative, and antispasmodic. After 30 minutes of balance period, concentrationrelated inhibitory effects on spontaneous contractions of morphine and meperidine were observed by administering agents to the organ baths in a cumulatively increasing manner from 10. Find patient medical information for meperidine injection on webmd including its uses, side effects and safety, interactions, pictures, warnings and user ratings. By continuing to browse this site you are agreeing to our use of cookies.
Letter to the editor regarding meperidine prescriptions in queensland, australia, 1999 to 2010. Figure 1 shows the total number of meperidine prescriptions issued. This policy has been approved by the medical executive committee. Product name meperidine hydrochloride injection, usp synonyms ethyl 1methyl4phenylisonipecotate hydrochloride 2. Abuse of meperidine poses a risk of overdose and death. Meperidine belongs to a class of drugs known as opioid narcotic analgesics and is similar to morphine. Meperidine hydrochloride tablets have been reported as being abused by crushing, chewing, snorting, or injecting the dissolved product. Meperidine hydrochloride tablets and oral solution are for oral use only. Meperidine was initially synthesized as an anticholinergic agent but was soon discovered to have analgesic properties. Meperidine definition of meperidine by the free dictionary. Meperidine article about meperidine by the free dictionary.
Dec 10, 2018 meperidine hydrochloride injection is indicated for preoperative medication, support of anesthesia, for obstetrical analgesia, and for the management of pain severe enough to require an opioid analgesic and for which alternative treatments are inadequate. Definition noun a synthetic narcotic drug trade name demerol used to treat pain synonyms. Optimize concomitant use of other appropriate therapies. Find out information about meperidine hydrochloride. It is also used for controlling post anesthetic shivering. Meperidine hydrochloride injection usp is indicated for the relief of acute episodes of moderate to severe. C15h21no2 a narcotic compound that is used medicinally as an analgesic and. Meperidine definition of meperidine by merriamwebster. We also have lists of words that end with meperidine, and words that start with meperidine. Meperidine is metabolized extensively in the human liver by 1 ndemethylation to.
Dailymed meperidine hydrochloride tablet meperidine. C15h21no2 a narcotic compound that is used medicinally as an analgesic and sedative explanation of meperidine hydrochloride. Meperidine meperidine is a 10 letter word starting with m and ending with e synonyms, crossword answers and other related words for meperidine. Meperidine demerol criteria for prescribing in an effort to ensure safe use of meperidine within our facility, a policy has been developed outlining appropriate criteria for usage. Pronunciation of meperidine with 2 audio pronunciations, 3 synonyms, 9 translations and more for meperidine. Its main pharmacological action is produced through. Meperidine hydrochloride monograph for professionals. Keep the medication in a place where others cannot get to it.
Jun 03, 2019 meperidine hydrochloride preparations are subject to control under the federal controlled substances act of 1970 as schedule ii cii drugs. A meperidine overdose can be fatal, especially in a child or other person using the medicine without a prescription. A list of words that contain meperidine, and words with meperidine in them. Demerol is the brand name of the prescription drug meperidine. Meperidine definition and meaning collins english dictionary. Use other narcotic medications that provide adequate pain relief without these risks. Find patient medical information for meperidine oral on webmd including its uses, side effects and safety, interactions, pictures, warnings and user ratings. There are many historical factors that led to meperidine being established as a standard agent for pain relief, but there are no valid reasons for its continued status as a first line agent in analgesia and many reasons why it should not be used routinely. Meperidine is metabolized chiefly in the liver, with a halflife of 3 hours. The drug has been used to relieve the pain of myocardial infarction, although it is probably not as effective as morphine sulfate. We hope that the following list of synonyms for the word meperidine will help you to finish your crossword today. It is an opioid analgesic, and thus its effects on the body resemble those of opium or morphine, one of opiums purified constituents. In patients with cirrhosis, the bioavailability of meperidine is increased to as much as 80%, and the t12 of both meperidine and normeperidine are prolonged. Meperidine is a synthetic opioid analgesic frequently prescribed in the emergency department.
Meperidine hydrochloride is a prescription painkiller. Hazards identification emergency overview meperidine hydrochloride injection, usp is a solution containing meperidine hydrochloride, a narcotic analgesic which produces analgesia and sedation. Drug information on demerol hcl meperidine includes side effects, uses, drug interactions, dosage, drug pictures, overdose symptoms, and what to avoid. Look up information on diseases, tests, and procedures. Longterm or regular use of opioid drugs like meperidine injection may lead to dependence. Generally limit to shortterm use a few days because of risk of accumulation of toxic normeperidine metabolite with repeated or large doses. Call your doctor if meperidine injection stops working well. Meperidine is a synthetic piperidine ester with opioid analgesic activity. Apr 18, 2020 meperidine hydrochloride tablets and oral solution are for oral use only. Meperidine definition, a narcotic compound, c15h21no2, used as an analgesic and sedative. Find 6 synonyms for meperidine and other similar words that you can use instead from our thesaurus. Meperidine definition of meperidine by medical dictionary. Pethidine, also known as meperidine and sold under the brand name demerol among others, is a synthetic opioid pain medication of the phenylpiperidine class. A read is counted each time someone views a publication summary such as the title, abstract, and list of authors, clicks on a figure, or views or downloads the fulltext.
Demerol meperidine side effects, dosage, interactions. Meperidine hydrochloride dosage and administration general. Normeperidine synonyms, normeperidine pronunciation, normeperidine translation, english dictionary definition of normeperidine. Topics az slideshows images quizzes supplements medications. Background meperidine pethidine is an opioid analgesic that offers little advantage relative to other opioids and several disadvantages including limited potency, short duration of action, and. Nov 07, 2019 meperidine is an opioid medication used to treat moderate to severe pain. Demerol is a strong prescription pain medicine that is used to manage the relief shortterm pain, when other pain treatments such as nonopioid pain medicines do not treat your pain well enough or you cannot tolerate them careless use of demerol can put you at risk of overdose and death. Meperidine, synthetic drug used in the treatment of moderate to severe pain. Addiction may occur in patients who obtain meperidine illicitly or in those appropriately prescribed the drug.
Identification of the substancemixture and of the companyundertaking. Meperidine is a strong analgesic used in the relief of moderate to severe pain. Meperidine may also be used for purposes not listed in this medication guide. Noun a fastacting opioid analgesic drug used in the treatment of severe pain. Overdose symptoms may include slow breathing and heart rate, severe drowsiness, muscle weakness, cold and clammy skin, bluecolored skin or lips, fainting, or coma. Normeperidine definition of normeperidine by the free. Nalbuphine versus meperidine for postoperative analgesia. Meperidine also is used parenterally for preoperative sedation, as a supplement to anesthesia, and to provide analgesia during labor. Meperidine is an opioid medication used to treat moderatetosevere pain.
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